The RNF139 Conjugated Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to RNF122. This antibody recognizes Human antigen. The RNF139 Conjugated Antibody has been shown to work in the following applications: Other.
Description
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP