The Rabbit Anti-Otpb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The Rabbit Anti-Otpb Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved Nglycosylation site. Glycosylation of the Fc fragment is essential for Fc receptormediated activity. The N-glycans attached to this site are predominantly corefucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and ?? -2,6 linked sialic acid residues