The eIF4ENIF1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to EIF4ENIF1. This antibody recognizes Human, Mouse, Rat, and Non-Human Primate antigen. The eIF4ENIF1 Antibody has been shown to work in the following applications: EIA, Immunoassay, and ELISA.
Description
Function: Nucleoplasmic shuttling protein, which inhibits translation initiation. Mediates the nuclear import of EIF4E by a piggy-back mechanism.
Subcellular Location: Cytoplasm. Nucleus. Nucleus>PML body. Nucleus speckle. Note: Predominantly cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Localization to nuclear foci and speckles requires active transcription.
Tissue Specificity: Widely expressed.
Subunit Structure: Interacts with EIF4E. Interacts with importin beta only in the presence of importin alpha, suggesting a direct interaction with importin alpha. Interacts with APOBEC3G in an RNA-dependent manner