MyBioSource.com's Anti-Ms LPAM-1 Purified Azide Free is a Rat monoclonal antibody. It reacts with Mouse. This antibody has been shown to work in applications such as: Cell Sorting, Isolation, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - frozen, and Immunoprecipitation.
Description
Integrin alpha 4/beta 7 (CD49d/Ly69), also known as LPAM-1 (Lymphocyte Peyer's patch adhesion molecule 1), is a heterodimeric (150kDa/130kDa) integrin complex which mediates lymphocyte homing to Peyer's patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion