The Anti-Ms LPAM-1 Purified Antibody from MyBioSource.com is a Rat Monoclonal antibody. This antibody recognizes Mouse antigen. The Anti-Ms LPAM-1 Purified Antibody has been shown to work in the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry - frozen, and Immunoprecipitation.
Description
Integrin alpha 4 / beta 7 (CD49d / Ly69), also known as LPAM-1 (Lymphocyte Peyer's patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer's patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion