The Rabbit Anti-Nociceptin receptor Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to OPRL1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Nociceptin receptor Antibody has been shown to work in the following applications: Immunofluorescence.
Description
G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin