MyBioSource.com's SETDB1 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot. The SETDB1 Polyclonal Antibody was generated using SET domain bifurcated histone lysine methyltransferase 1, and SETDB1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described