The WWOX Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to WWOX. This antibody recognizes Human antigen. The WWOX Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants