The BMP2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BMP2, and Bone Morphogenetic Protein 2. This antibody recognizes Human, Mouse, and Rat antigen. The BMP2 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction