MyBioSource.com's Insulin Degrading Enzyme/IDE Rabbit mAb is a Rabbit monoclonal antibody. The Insulin Degrading Enzyme/IDE Rabbit mAb Antibody was generated using IDE, and insulin degrading enzyme as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot.
Description
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid