MyBioSource.com's Rabbit Anti-FABP5 Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-FABP5 Antibody was generated using FABP5 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential