MyBioSource.com's Cyclin B2/CCNB2 Rabbit mAb is a Rabbit monoclonal antibody. The Cyclin B2/CCNB2 Rabbit mAb Antibody was generated using CCNB2, and Cyclin B2 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, Immunoprecipitation, and Western Blot.
Description
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]