MyBioSource.com's PI 3 Kinase p85 alpha Rabbit mAb is a Rabbit monoclonal antibody. The PI 3 Kinase p85 alpha Rabbit mAb Antibody was generated using PIK3R1 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Western Blot.
Description
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]