MyBioSource.com's Anti-RUNX1 Mouse mAb is a Mouse monoclonal antibody. The Anti-RUNX1 Mouse mAb Antibody was generated using RUNX family transcription factor 1, and RUNX1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Western Blot.
Description
Entrez Summary: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood