MyBioSource.com's Heme Oxygenase 1 Rabbit mAb is a Rabbit monoclonal antibody. The Heme Oxygenase 1 Rabbit mAb Antibody was generated using Heme Oxygenase 1, and HMOX1 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis