The ESRRA Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ESRRA, and Estrogen Related Receptor alpha. This antibody recognizes Human, Mouse, and Rat antigen. The ESRRA Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene