MyBioSource.com's eIF4A1 Mouse mAb is a Mouse monoclonal antibody. The eIF4A1 Mouse mAb Antibody was generated using EIF4A1 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA-this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression