The PTPN22 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to protein tyrosine phosphatase non-receptor type 22, and PTPN22. This antibody recognizes Human, Mouse, and Rat antigen. The PTPN22 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described