The ASPN Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ASPN, and Asporin. This antibody recognizes Human, Mouse, and Rat antigen. The ASPN Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence.
Description
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants