MyBioSource.com's Tryptophanyl tRNA Synthetase/WRS Rabbit mAb is a Rabbit monoclonal antibody. The Tryptophanyl tRNA Synthetase/WRS Rabbit mAb Antibody was generated using tryptophanyl-tRNA synthetase 1, and WARS1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression