The Geminin Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to geminin DNA replication inhibitor. This antibody recognizes Human antigen. The Geminin Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control