The Rabbit Anti-PIN1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PIN1. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-PIN1 Antibody has been shown to work in the following applications: Other.
Description
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner