The CLDN6 Mouse mAb Antibody from MyBioSource.com is a Mouse Monoclonal antibody to Claudin 6, and Cldn6. This antibody recognizes Human, Mouse, and Rat antigen. The CLDN6 Mouse mAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Function: Plays a major role in tight junction-specific obliteration of the intercellular space.(Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.
Subcellular Location: Cell junction>Tight junction. Cell membrane>Multi-pass membrane protein.
Tissue Specificity: Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.
Subunit Structure: Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3 (By similarity). Interacts with CLDN1, CD81 and OCLN (PubMed:20375010).
Similarity: Belongs to the claudin family