The GCSH Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GCSH. This antibody recognizes Human, Mouse, and Rat antigen. The GCSH Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Immunohistochemistry.
Description
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome