The ITGB4 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ITGB4. This antibody recognizes Human, and Mouse antigen. The ITGB4 Rabbit pAb Antibody has been shown to work in the following applications: Western Blot.
Description
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760)