The MRC2 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Mannose Receptor C Type 2, and MRC2. This antibody recognizes Human, and Mouse antigen. The MRC2 Rabbit pAb Antibody has been shown to work in the following applications: Western Blot.
Description
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs)