MyBioSource.com's Rabbit Anti-Rho Guanine nucleotide Exchange Factor 7 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Other. The Rabbit Anti-Rho Guanine nucleotide Exchange Factor 7 Antibody was generated using ARHGEF7 as the antigen and it reacts with Human.
Description
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions by similarity. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons