The DUSP6/MKP3 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to DUSP6. This antibody recognizes Human, Mouse, and Rat antigen. The DUSP6/MKP3 Rabbit pAb Antibody has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Inactivates MAP kinases. Has a specificity for the ERK family (PubMed: 9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain