The Phospho-RUNX1-S249 pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to RUNX family transcription factor 1, and RUNX1. This antibody recognizes Human antigen. The Phospho-RUNX1-S249 pAb Antibody has been shown to work in the following applications: Western Blot.
Description
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene