The Anti-Hu CD261 APC Antibody from MyBioSource.com is a Mouse Monoclonal antibody to TNFRSF10A. This antibody recognizes Human antigen. The Anti-Hu CD261 APC Antibody has been shown to work in the following applications: Flow Cytometry.
Description
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor)