MyBioSource.com's Geminin Rabbit pAb is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot. The Geminin Rabbit pAb Antibody was generated using geminin DNA replication inhibitor as the antigen and it reacts with Human.
Description
Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control