The SDHD Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SDHD. This antibody recognizes Mouse antigen. The SDHD Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants