The Rabbit Anti-EpCAM/CD326 Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to EPCAM, and epithelial cell adhesion molecule. This antibody recognizes Human, Canine, and Feline antigen. The Rabbit Anti-EpCAM/CD326 Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Epitope of this MAb is mapped between aa 202-212 of EGP40, which is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. Antibody to Ep-CAM has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma