MyBioSource.com's Rabbit Anti-Bcl-2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry. The Rabbit Anti-Bcl-2 Antibody was generated using BCL2, and BCL2 apoptosis regulator as the antigen and it reacts with Human.
Description
Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t (14; 18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line