The Rabbit Anti-IGF-I Receptor beta Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to IGF1R. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-IGF-I Receptor beta Antibody has been shown to work in the following applications: Western Blot.
Description
insulin like growth factor 1 receptor (IGF1R), Homo sapiens. This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]