MyBioSource.com's Anti-Hu CD38 APC is a Mouse monoclonal antibody. The Anti-Hu CD38 APC Antibody was generated using CD38 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration