The NAK/TBK1 (N-Term) Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TBK1. This antibody recognizes Human, Mouse, and Rat antigen. The NAK/TBK1 (N-Term) Rabbit pAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex