The Rabbit Anti-Caspase 9 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CASP9, and Caspase 9. This antibody recognizes Human, Mouse, Rat, and Canine antigen. The Rabbit Anti-Caspase 9 Antibody has been shown to work in the following applications: Flow Cytometry, and Immunofluorescence.
Description
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1 c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9