The ITPR1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ITPR1. This antibody recognizes Human, Mouse, and Rat antigen. The ITPR1 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene