Dab1(Phospho-Tyr220) Rabbit Polyclonal Antibody from Bioassay Technology Laboratory

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice: the disabled-1 gene plays a central role in brain development: directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1: and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported: but their full length nature has not been determined