The Rpb1(Phospho Ser1619) Polyclonal Antibody from Bioassay Technology Laboratory is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, Rat, and Non-Human Primate antigen. The Rpb1(Phospho Ser1619) Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
This gene encodes the largest subunit of RNA polymerase II: the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition: this subunit: in combination with several other polymerase subunits: forms the DNA binding domain of the polymerase: a groove in which the DNA template is transcribed into RNA