SGCG Rabbit Polyclonal Antibody from Bioassay Technology Laboratory

This gene encodes gamma-sarcoglycan: one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin: syntrophin: alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy: in particular limb-girdle muscular dystrophy: type 2C (LGMD2C)