Bioassay Technology Laboratory's Dab1(Phospho Tyr220) Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot.
Description
The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.:Adapter molecule functioning in neural development. May regulate SIAH1 activity.:PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.:Contains 1 PID domain.:subunit:Associates with the SH2 domains of SRC: FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.: