Bioassay Technology Laboratory's RSK3(Phospho Thr353) Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot.
Description
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.:cofactor:Magnesium.:enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.:PTM:Autophosphorylated on Ser-377: as part of the activation process.:Belongs to the protein kinase superfamily.:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.:Contains 1 AGC-kinase C-terminal domain.:Contains 2 protein kinase domains.:subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.:tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.: