DHX16 Rabbit Polyclonal Antibody from Bioassay Technology Laboratory

DEAD box proteins: characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD): are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation: nuclear and mitochondrial splicing: and ribosome and spliceosome assembly. Based on their distribution patterns: some members of this family are believed to be involved in embryogenesis: spermatogenesis: and cellular growth and division. This gene encodes a DEAD box protein: which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3: a region where many malignant: genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene