Bioassay Technology Laboratory's VEGF Receptor 2(Phospho-Tyr951) Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor: known as kinase insert domain receptor: is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation: survival: migration: tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors: including Rab GTPase: P2Y purine nucleotide receptor: integrin alphaVbeta3: T-cell protein tyrosine phosphatase: etc. Mutations of this gene are implicated in infantile capillary hemangiomas