The RFX6 Rabbit Polyclonal Antibody from Bioassay Technology Laboratory is a Rabbit Polyclonal antibody. This antibody recognizes Human, and Mouse antigen. The RFX6 Rabbit Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin: but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function: thus: restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome: which is characterized by neonatal diabetes with pancreatic hypoplasia: duodenal and jejunal atresia: and gall bladder agenesis