The GPIX Polyclonal Antibody from Bioassay Technology Laboratory is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The GPIX Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency