Bioassay Technology Laboratory's Rpb1 CTD(Phospho-Ser2) Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
This gene encodes the largest subunit of RNA polymerase II: the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition: this subunit: in combination with several other polymerase subunits: forms the DNA binding domain of the polymerase: a groove in which the DNA template is transcribed into RNA