Bioassay Technology Laboratory's PDGF Receptor alpha(Phospho-Tyr1018) Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer: composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development: wound healing: and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome: somatic and familial gastrointestinal stromal tumors: and a variety of other cancers